Products that safely eliminate pathogen carriage in livestock


General Probiotics (GP) is a University of Minnesota start-up. We develop advanced probiotics, a new antimicrobial technology for farmers to eliminate pathogens in livestock. Our products will result in healthier animals, in higher productivity for farmers, and in safer food for consumers.

GP engineers are world leaders in probiotics, with the expertise to boost the natural capacity of probiotics to exterminate pathogens. Our advanced probiotics eliminate pathogens more effectively and reliably than any currently marketed probiotic. Our technology is scientifically proven and is covered by three patent applications.

We have been awarded Phase I and Phase II Small Business Innovative Research grants (a total of $825k), in order to pursue an unparalleled R&D program and to commercialize new antimicrobials.

Background and Products/Services

capture1General Probiotics develops antimicrobial technologies. Our products eliminate pathogens in food-producing animals. Experiments have demonstrated that our products can eliminate 97% of salmonella in pre-harvest poultry.

With proprietary technologies first developed at the University of Minnesota, we develop products to fight bacterial infections, secure food production, and eliminate the overuse of antibiotics in livestock production.

We are first focusing on chickens because poultry are a significant source of animal protein, with per capita consumption in the US doubling to nearly 90 lbs/year since 1980. This agricultural sector is also of particular interest because despite the vast arsenal of technologies employed to control salmonella in poultry products, poultry meat and eggs are the most important reservoir of zoonotic Salmonella enterica.

We recently completed our first large-scale animal study. The results are published in Nature’s Scientific Reports ( We successfully designed, built and tested antimicrobial probiotics in turkey poults. We have shown that our technology eliminates 97% of Salmonella enterica from the ceca in the GI tract of treated birds. Salmonella is the number one foodborne pathogen. Poultry is the number one source of salmonella. The ceca is the main repository of salmonella in poultry. This proof-of-concept demonstration paves the way for more animal studies and preclinical trials.


fda-logo-usdaChicken producers need antimicrobial technologies to eliminate pathogenic microbes in chicken. They need antimicrobial technologies to produce healthy chicken flocks and to eliminate the risk of contaminated meat they sell. They need antimicrobial technologies to defend product brand, meet USDA inspection standards, meet FDA food safety standards, and to mitigate recall and litigation risk.

We develop an antimicrobial technology that eliminates pathogens in chickens. Our products will help chicken producers produce and distribute whole chickens and chicken parts that are not contaminated with salmonella, clostridia or campylobacter. Our products will help chicken producers defend and maintain the integrity of their brand. Our products will lower the risk of foodborne infection outbreaks, lower the risk of chicken product recalls, and lower the risk of litigation against chicken producers in the event of an outbreak. Our product will help ensure the supply of safe food to consumers.

Status and Forecast

nsfGeneral Probiotics has received Small Business Innovative Research grants from the US National Science Foundation. We are operating at University Enterprise Laboratories with two engineers and the chief executive office. General Probiotics is licensing technology from the University of Minnesota and is seeking strategic partners and early-stage investors.

General Probiotics, Inc. is participating in the 2017 MNCup competition

General Probiotics, Inc.
1000 Westgate Drive, Suite 122
St. Paul, MN 55114

Visit us on Twitter @GenProbiotics