Advanced probiotics

We have the solution that farmers need to raise healthy animals, free of foodborne illnesses. The antimicrobial technology developed at General Probiotics is unique in its high and consistent performance.

We engineer probiotics to express and secrete antimicrobial peptides. We target pathogens in livestock.

Probiotics are bacteria that are generally regarded as safe to use. They are bile resistant and can reach the intestines of animals. Probiotics confer benefits, including antimicrobial activity. But their performance is not consistent. The FDA states that claims for probiotics and direct-fed microbials are often not supported by science.

At General Probiotics we engineer probiotics for consistent, therapeutic performance. With combined expertise of more than 30 years, we create and leverage synergies between artificial intelligence and a new generation of synthetic biology techniques to develop innovative therapeutics and prophylactics for E. coli, Salmonella, Enterococcus, Lawsonia, Staphylococcus, Listeria, Clostridia and Campylobacter.

We have significant proof of concept animal results, lowering counts of pathogens in the gastrointestinal tract of livestock.

Over 2 million people are sickened in the US by multidrug-resistant infections and over 23,000 die every year. One significant cause of drug-resistance emergence is the widespread use of antibiotics in farm animal production: in 2012, over 32 million pounds of antibiotics, or 68% of all antibiotics sold in the US, were administered to animals. Antibiotics are administered to humans only by prescription, but 97% of antibiotics used in food-producing animals were sold over the counter (OTC). This uncontrollable overuse breeds “superbugs”, microbes that resist all antibiotics.

In 2017, the FDA banned the widespread practice of OTC antibiotics. This withdrawal of antibiotics from animal production is a step in the right direction, but it poses a major threat to the industry in the case of a bacterial disease outbreak. Farmers now urgently need new antimicrobials to raise healthy livestock and to produce safe food.

GP is developing a line of antimicrobial probiotics that target pathogens in chickens and pigs. With GP probiotics farmers can raise livestock sustainably.